1H-Pyrrolo[2,3-B]pyridine-5-Amine
1H-Pyrrolo[2,3-B]pyridin-5-ylamine
CAS: 100960-07-4
Molecular Formula: C7H7N3
1H-Pyrrolo[2,3-B]pyridine-5-Amine - Names and Identifiers
| Name | 1H-Pyrrolo[2,3-B]pyridin-5-ylamine |
| Synonyms | 5-Amino-7-Azaindole 5-AMINO-7-AZAINDOLE 5-AMino-7-aza-1H-indole 1H-Pyrrolo[2,3-B]pyridin-5-Amine 1H-PYRROLO[2,3-B]PYRIDIN-5-AMINE 1H-PYRROLO[2,3-B]PYRIDINE-5-AMINE 1H-Pyrrolo[2,3-B]pyridine-5-Amine 5-Amino-1H-pyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridin-5-ylaMine 1H-Pyrrolo[2,3-b]pyridine,5-amino- 1H-Pyrrolo[2,3-B]pyridin-5-ylamine 1H-PYRROLO[2,3-B]PYRIDIN-5-YLAMINE 1H-Pyrrolo[2,3-b]pyridine,5-amino-(6CI) |
| CAS | 100960-07-4 |
| InChI | InChI=1/C7H7N3/c8-6-3-5-1-2-9-7(5)10-4-6/h1-4H,8H2,(H,9,10) |
| InChIKey | PLWBENCHEUFMTN-UHFFFAOYSA-N |
1H-Pyrrolo[2,3-B]pyridine-5-Amine - Physico-chemical Properties
| Molecular Formula | C7H7N3 |
| Molar Mass | 133.15 |
| Density | 1.41±0.1 g/cm3(Predicted) |
| Melting Point | 128-129°C |
| Boling Point | 361.7±35.0 °C(Predicted) |
| Appearance | Solid |
| Color | Yellow to yellow/brown |
| pKa | 8.28±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Light Sensitive |
| Refractive Index | 1.78 |
1H-Pyrrolo[2,3-B]pyridine-5-Amine - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
1H-Pyrrolo[2,3-B]pyridine-5-Amine - Introduction
1H-pyrrolo [2,3-b] pyridin -5-amine is an organic compound with the chemical formula C10H8N2. It has the form of a white to pale yellow crystalline solid.
The compound is commonly used as an important raw material for pharmaceutical intermediates and organic synthesis. It can be used in the pharmaceutical field to synthesize anti-tumor drugs, antidepressants, antipsychotics, etc. In addition, it can also be used as a synthetic raw material for dyes and photosensitizers.
The preparation of 1H-pyrrolo [2,3-b] pyridin -5-amine can be carried out by various routes. A common synthetic method is the reaction of pyrrolo [2,3-b] pyridines with the corresponding substituted amines under basic conditions. The reaction is usually carried out in an organic solvent, and temperature and reaction time are controlled.
Regarding safety information, 1H-pyrrolo [2,3-b] pyridin -5-amine is less toxic, but care should be taken to follow routine laboratory safety procedures. Wear protective glasses and gloves during operation to avoid direct contact with skin and inhalation of dust. In case of accidental contact or ingestion, seek medical attention immediately and bring the label or information of the relevant compound.
The above is an introduction to the basic properties, uses, preparation methods and safety information of 1H-pyrrolo [2,3-b] pyridin -5-amine.
The compound is commonly used as an important raw material for pharmaceutical intermediates and organic synthesis. It can be used in the pharmaceutical field to synthesize anti-tumor drugs, antidepressants, antipsychotics, etc. In addition, it can also be used as a synthetic raw material for dyes and photosensitizers.
The preparation of 1H-pyrrolo [2,3-b] pyridin -5-amine can be carried out by various routes. A common synthetic method is the reaction of pyrrolo [2,3-b] pyridines with the corresponding substituted amines under basic conditions. The reaction is usually carried out in an organic solvent, and temperature and reaction time are controlled.
Regarding safety information, 1H-pyrrolo [2,3-b] pyridin -5-amine is less toxic, but care should be taken to follow routine laboratory safety procedures. Wear protective glasses and gloves during operation to avoid direct contact with skin and inhalation of dust. In case of accidental contact or ingestion, seek medical attention immediately and bring the label or information of the relevant compound.
The above is an introduction to the basic properties, uses, preparation methods and safety information of 1H-pyrrolo [2,3-b] pyridin -5-amine.
Last Update：2024-04-09 20:52:54
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